Evolución de la leucemia linfoblástica aguda en la edad pediátrica en 29 años ( )Outcome of acute lymphoblastic leukemia in the pediatric age group . La leucemia linfoblástica aguda (LLA) es el cáncer más común en los niños y está entre los más curables de las malignidades pediátricas. El análisis citogenético de las células blásticas en niños con leucemia linfoblástica aguda (LLA) ha permitido el reconocimiento de alteraciones cromosómicas.

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J Pediatr Hematol Oncol ; This study focuses on the most important chromosomal abnormalities found in childhood ALL and their prognostic and therapeutic implications.

Hyperdiploid acute lymphoblastic leukemia in children. Immunology of Down syndrome. Abnormal serum IgG subclass pattern in children with Down’s syndrome.

Factores de riesgo para la leucemia linfocítica aguda

Leukemia ; 12 5: J Clin Oncol, 12pp. Increased incidence of spontaneus apoptosis in the bone marrow of hyperdiploid chilhood acute lymphoblastic leukemia.


Clonal hematologic disorders in Down syndrome. A Pediatric Oncology Group Study. Cytogenetic and molecular studies of Down syndrome individuals with leukemia. Fusion with EA2 converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the 1; Proposal for the immunological classification of acute leukemias. Clinical and cytogenetic characteristics and treatment outcome: Blood, 79pp. Epub Sep Pediatr Hematol Oncol ; 9: Blood, 87pp.

J Pediatr ; Heterogeneity of presenting features and their relation to treatment outcome leuceima clildren with T-cell acute lymphoblastic leukemia. The formation of trisomies and their parental origin in hyperdiploid chilhood acute lymphoblastic leukemia.

Am Med Genet Suppl ; 7: Collaborative study of karyotypes in childhood acute lymphoblastic leukemia.

Factores de riesgo para la leucemia linfocítica aguda

Blood, 81pp. Prognostic implications of chromosomal findings in acute lymphoblastic leukemia at diagnosis. Cytogenetic abnormalities in acute lymphoblastic leukemia.

Down Syndrome, Drug Metabolism and Chromosome Unifirm approch to risk classification and treatment assignment to children with acute lymphoblastic leukemia. Clinical and biological characteristics of acute lymphocytic leukemia in children with Down syndrome. A mathematical model of in vivo methotreaxate accumulation in acute lymphoblastic leukemia.


Acute Leukemias in Children with Down Syndrome. Immunologic, cytogenetic, and clinical characterization of childhood acute lymphoblastic leukemia with the t 1;9 q23;p13 or its derivative.

Alteraciones cromosómicas en la leucemia linfoblástica aguda | Anales de Pediatría

Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia. You can change the settings or obtain more information by leucrmia here. Down syndrome and acute leukemia in children: Translocation t 9;22 is associated with extremely poor prognosis in intensively treated children with acute lymphoblastic leukemia.